Anatomy books

Wednesday, November 11, 2020

The dorsal column–medial lemniscus pathway

The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway, PCML) is a sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception(position) from the skin and joints. It transmits information from the body to the primary somatosensory cortex in the postcentral gyrus of the parietal lobe of the brain.

 The pathway receives information from sensory receptors (missner’s corpuscle, pacinian corpuscle etc.) throughout the body, and carries this in nerve tracts in the white matter of the dorsal columns of the spinal cord to the medulla, where it is continued in the medial lemniscuses, on to the thalamus and relayed from there through the internal capsule and transmitted to the somatosensory cortex.

The name dorsal-column medial lemniscus comes from the two structures that carry the sensory information: the dorsal columns of the spinal cord, and the medial lemniscus in the brainstem.

There are three groupings of neurons that are involved in the pathway: first-order neurons, second-order neurons, and third-order neurons.

 The first-order neurons are sensory neurons located in the dorsal root ganglia, that send their afferent fibers through the two dorsal columns – the gracile fasciculus, or gracile tract, and the cuneate fasciculus, or cuneate tract. The first-order axons make contact with second-order neurons of the dorsal column nuclei (the gracile nucleus and the cuneate nucleus) in the lower medulla.

The second-order neurons send their axons to the thalamus.

The third-order neurons are in the ventral nuclear group in the thalamus and fibres from these ascend to the postcentral gyrus.

Sensory information from the upper half of the body is received at the cervical level of the spinal cord and carried in the cuneate tract, and information from the lower body is received at the lumbar level and carried in the gracile tract. The gracile tract is medial to the more lateral cuneate tract.

The axons of second-order neurons of the gracile and cuneate nuclei are known as the internal arcuate fibers and when they cross over the midline, at the sensory decussation in the medulla, they form the medial lemniscus which connects with thalamus; the axons synapse on neurons in the ventral nuclear group which then send axons to the postcentral gyrus in the parietal lobe. All of the axons in the DCML pathway are rapidly conducting, large, myelinated fibers.

 

Tuesday, November 10, 2020

Lateral spinothalamic tract

 

The lateral spinothalamic tract, also known as the lateral spinothalamic fasciculus, is an ascending pathway located anterolaterally within the peripheral white matter of the spinal cord. It is primarily responsible for transmitting pain and temperature as well as coarse touch. 

The anterior spinothalamic tract (discussed separately), in contrast, primarily transmits coarse touch and pressure. 

First-order neurons, whose cell bodies are in the dorsal root ganglion and whose axons extend from peripheral receptors, enter the cord via dorsal nerve roots. 

First-order neurons synapse with second-order neurons whose bodies are located in the ipsilateral substantia gelatinosa of dorsal horn of the spinal cord.

The lateral spinothalamic tract then ascends in the lateral funiculus, just medial to the ventral spinocerebellar tract. Fibers of this tract are somatotopically organized for their entire course.

Upon reaching the brainstem, the lateral and anterior spinothalamic tracts combine to form the spinal lemniscus, which runs lateral to the medial lemniscus

 The spinal lemniscus terminates in the ventral posterior nucleus of the thalamus. Here, it synapses with third-order neurons, which project to the primary somatosensory area on the ipsilateral side of the cerebral cortex.

Lesion : 


Contra-lateral loss of pain & thermal sensibilities below the level of the lesion

Unable to sense pin prick or recognize hot or cold objects 

Monday, November 9, 2020

Summary of Somatosensory pathways: lateral & anterior spinothalamic tract and tract of gall and cuneatus

Summary of Somatosensory pathways

The somatosensory system is a part of the sensory nervous system.

It  is a complex system of sensory neurons and neural pathways that responds to changes at the external environment or inside the body.

The axons (as afferent nerve fibers) of sensory neurons has two part peripheral and center part. Terminal portion of peripheral portion of axon of sensory neuron is converted into receptors.

 Sensory receptors are found all over the body including the skin, epithelial tissues, muscles, bones and joints, internal organs, and the cardiovascular system.

Touch is a crucial means of receiving information. This photo shows tactile markings identifying stairs for visually impaired people.

Somatic senses are sometimes referred to as somesthetic senses, with the understanding that somesthesis includes the sense of touch, proprioception (sense of position and movement), and (depending on usage) haptic perception

The mapping of the body surfaces in the brain is called somatotopy. In the cortex, it is also referred to as the cortical homunculus. This brain-surface ("cortical") map is not immutable, however. Dramatic shifts can occur in response to stroke or injury.

Our nervous system deal two types of sensation conscious and unconscious . this article summarized the main somatosensory pathways 


Topics

Lateral spino-thalamic tract  

Anterior spinothalamic tract

Tract of gracilis & cuneatus

Sensation

Pain and temperature

Light touch and pressure

Discriminative touch, vibration , conscious muscle joint sense

Receptor

Free nerve ending

Free nerve ending

Meissners corpuscles, pacinian corpuscles, muscle spindles , tendon organ

1st order neuron

Posterior root ganglion

Posterior root ganglion

Posterior root ganglion

2nd order neuron

Substantia getalinosa

Substantia getalinosa

Nuclei gracilis and nuceatus

3rd order neuron

Ventral posterior lateral nucleus of thalamus

Ventral posterior lateral nucleus of thalamus

Ventral posterior lateral nucleus of thalamus

Related with Spinal lamniscus

Present

Present

Absent

Related with Medial lamniscus

Absent

Absent

Present

Destination

Post central gyrus

Post central gyrus

Post central gyrus

 

Lesion

Contra-lateral loss of pain and thermal sensibilities below the level of the lesion

Unable to sense pin prick or recognize hot or cold objects

Contra-lateral loss of light touch and pressure  sensibilities below the level of the lesion.

Discriminative touch will be present but unable to feel light touch of cotton placed against the skin  

Ipsilateral loss of muscle and joint sensation, two point discrimination and vibration  below the level of lesion but sense of light touch is unaffected

Movement are jerky or ataxic