Seminiferous Epithelium/ sertoli cells

Seminiferous Epithelium/ sertoli cells
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The seminiferous epithelium is composed of sustentacular Sertoli cells and a stratified layer of developing malegametes. Sertoli cells establish a blood-testis barrier by forming occluding junctions with each other, thus subdividing the seminiferous tubule into adluminal and basal compartments. The basal compartment houses spermatogonia A (both light and dark), spermatogonia B, and the basal aspects of Sertoli cells.

 The adluminal compartment contains the apical portions of Sertoli cells, primary spermatocytes, secondary spermatocytes, spermatids,and spermatozoa. Spermatogenic cells, which regularly replicate and differentiate into mature sperm. These cells are derived from primordial germ cells originating in the yolk sac that colonize the gonadal ridges during early development of the testis.

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