Lymph node
Lymph nodes are small encapsulated organs located
along the pathway of lymphatic vessels
Diameter: 1mm to 2 cm
Two types of lymphatic vessels
are connected with lymph node: they are –
1. Afferent lymph vessels:
convey lymph toward the L. node and penetrate the capsule at multiple sites.
2. Efferent lymph vessels: convey lymph away from the lymph
node and leave at the hilum. It is one in number.
- Filter
the lymph
- 2.Produce
lymphocytes
- 3.
Initiation of immune responses
- 4.phagocytosis
Histological features of
Lymph node:
- capsule
is present
- sub-capsular
sinus is present
- Outer
cortex contains lymphatic nodules. Superficial part of cortex contain B lymphocytes and
deeper zone of cortex contain T lymphocyte
- inner
medulla contain medullary cord which composed of B lymphocyte
and plasma cells
Cells present within the
lymph nodes:
1.T & B lymphocyte,
2.dendritic cells,
3.macrophages
What is lymphatic nodule?
Ans: small collection of
lymphocytes found in mucosa of different organs like ileum, appendix, bronchus
etc.
Types of lymphatic nodule:
Primary and secondary lymphatic
nodules
When a germinal center appears in a
lymphatic nodule the lymphatic nodule known as secondary L nodule
What is germinal center:
It is a pale staining area situated within a lymphatic
nodule contain immature B lymphoblast.
Germinal centre found only in secondary lymphatic nodule.
What is trabeculea?
Ans: They are the part of capsule which enter in to the
organ
What do you mean by sinuses of lymph node?
Ans: these are empty spaces within a lymph node where
lymph flows.
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